Pre-symptomatic diagnosis in fatal familial insomnia: serial neurophysiological and FDG-PET studies
نویسندگان
چکیده
Department of Neuroscience, C.N.R.-I.B.F.M., Vita-Salute San Raffaele University, C.N.R.-I.B.F.M., University of Milan-Bicocca, Scientific Institute H. S. Raffaele, Milan, Department of Neurological Sciences, University of Bologna, DISMR, Department of Motor Sciences, Center for Sleep Medicine, University of Genova, Italy and Institute of Pathology, Case Western Reserve University, Cleveland, OH, USA
منابع مشابه
Pre-symptomatic diagnosis in fatal familial insomnia: serial neurophysiological and 18FDG-PET studies.
Knowing how and when the degenerative process starts is important in neurodegenerative diseases. We have addressed this issue in fatal familial insomnia (FFI) measuring the cerebral metabolic rate of glucose (CMRglc) with 2-[18F]fluoro-2-deoxy-D-glucose PET in parallel with detailed clinical, neuropsychological examinations and polysomnography with EEG spectral analyses. Nine asymptomatic carri...
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